Matthew Gedye
Graduate Researcher — Mitochondria, Exercise Physiology, Molecular Biology
IPAN · Deakin University  |  CFAS · University of Copenhagen
Matthew Gedye

About

I’m a graduate researcher in my final year of my PhD at Deakin University and the University of Copenhagen where my research sits at the intersection of exercise physiology and molecular biology. For my thesis, I’m investigating microRNAs (miRNAs) localised to the mitochondria of skeletal muscle and how physiology (exercise-induced) and pathology (type 1 diabetes) influence their expression with a combination of human, mouse and cell-based models. In addition, utilising bioinformatics, I’m exploring mechanisms to help explain how, which will hopefully help us to then understand why, these miRNAs localise to the mitochondria in the first place.

I’m fascinated by mitochondria. Not just for the role they play in metabolism, but in overall cellular function. I’m particularly interested in seeking to understand how the molecular events underpinning mitochondrial biology cascade upwards through cells, tissues, and systems to shape physiology and biology of whole organisms. I find myself drawn to the threads connecting these levels of organisation to biological anthropology, comparative physiology, evolutionary medicine, and bioinformatics. I have aspirations to work in, or adjacent to, these fields to contribute to an interdisciplinary framework to help combat metabolic disease.


News

July 2026 — Speaking at the European College of Sport Science (ECSS) Congress, Lausanne, Switzerland.

March 2026 — Relocated to Copenhagen to begin a research placement at CFAS, University of Copenhagen.


Education

PhD in Exercise Physiology and Molecular Genetics

Deakin University and the University of Copenhagen · November 2023 – present

Thesis: Investigating the mechanistic role of microRNAs localised to skeletal muscle mitochondria under physiological and pathological conditions

Supervisors: Prof. Glenn Wadley, Prof. Severine Lamon, Dr. Bianca Bernardo, A/Prof. Søren Neilsen

Master of Human Nutrition
Deakin University · 2020–2022
Bachelor of Health Science (Major in Physiology and Anatomy)
La Trobe University · 2012–2016

Publications

  1. Challenges and Future Prospectives in Circular RNA Investigation. Hiam D, Gedye MJ, Wadley GD, Bernardo BC. Adv Exp Med Biol. 2025;1485:467–479. — doi: 10.1007/978-981-96-9428-0_27 — Review.

  2. The Binding Properties of Antibodies to Z-DNA in the Sera of Normal Healthy Subjects. Pisetsky DS, Gedye MJ, David LA, Spencer DM. Int J Mol Sci. 2024 Feb 22;25(5):2556. — doi: 10.3390/ijms25052556


Research Career

Present (2023 – )
Graduate Researcher — Institute of Physical Activity & Nutrition (IPAN) · Deakin University, Australia
Centre for Physical Activity Research (CFAS) · University of Copenhagen Hospital, Rigshospitalet, Denmark (based at CFAS from March 2026)
Former (2022–2024)
Research Technician — David Lab: Department of Molecular Genetics & Microbiology · Duke University, United States

Skills


Affiliations & Collaborators

IPAN — Institute for Physical Activity and Nutrition
Deakin University, Australia
CFAS — Centre for Physical Activity Research
University of Copenhagen, Denmark
Australian Physiological Society
Student Representative, 2024 – present

Contact

I welcome enquiries from researchers, collaborators, and anyone curious about the work. Send me an email.

Personal site: gedye.me